Wednesday, July 23, 2008

More reasons to be concerned about those extra pounds, especially those that settle around the middle.People with a bulging waistline in mid-life could face a higher risk of dementia and Alzheimer’s in the senior years, a new study shows. "A large belly, independent of total weight, is a potent predictor of dementia," said Rachel A. Whitmer, a research scientist at the Kaiser Permanente Division of Research in Oakland, CA who led the new study. The findings are alarming in light of America's growing girth, Whitmer and other experts said.


"If these findings are replicated and better understood, it looks like an unhealthy brain could be another consequence of this epidemic of obesity," said Lenore Launer of the National Institute on Aging.

The research is the latest evidence that fat in the abdomen is the most dangerous kind. Previous studies have linked an apple-shaped physique to a greater propensity for diabetes, heart disease and stroke. Researchers suspect that belly fat cells are the worst because of their proximity to major organs. They ooze noxious chemicals, stoking inflammation, constricting blood vessels and triggering other processes that may also damage brain cells.

"There is a lot of work out there that suggests that the fat wrapped around your inner organs is much more metabolically active than other types of fat right under the skin," Whitmer said. "It's pumping out toxic substances. It's very potent toxic fat."

"What that tells you is the effect of the belly is over and above of being overweight," Whitmer said. "One of the take-home messages is it's not just your weight, but where you carry your weight in middle age, that is a strong predictor of dementia."

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posted by Sandy at 6:14 PM | 1 comments